Recently I've been using LYX with the foils package and compiling
using pdflatex and have found that the slides come out nicely. Here's
an example Lyx file.
I just create the pdf from the LYX file by exporting to Latex and
using pdflatex, or by exporting directly as pdf from within LYX
(which uses pdflatex).
My old way is illustrated in this example Latex file
for creating a presentation.