**A. Bureau, T. P. Speed**

**Week 9, Tuesday lecture: Monte Carlo methods in pedigree analysis**

For any type of computation over pedigrees, the complexity of the task may increase to the point where exact computation is no longer feasible. Monte Carlo methods then provide alternatives to estimate the statistic or probability of interests. Markov chain Monte Carlo (MCMC) is one of the most useful simulation techniques in statistical genetics, and we begin by reviewing its principles.

- Generic introduction to Markov chain Monte Carlo
- Early applications of Monte Carlo methods in pedigree analysis
- MCMC in pedigree analysis
- Difficulties with MCMC
- Further readings
- References
- About this document ...

Wed Apr 22 19:50:08 PDT 1998