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Home - Talks / Posters Basic microarray data questions
 
Title:  Basic microarray data questions

Speaker: Terry Speed

Place: Lorne Conference

Date: Feb. 11, 2000

Abstract:

The wealth of microarray-based gene expression data now available
poses many questions ranging from very basic ones such as finding the DNA
spots on the image and measuring their intensities, through to
classifying genes and seeking to elucidate biochemical pathways. Most
attention so far has been to clustering methods for grouping genes
and/or samples. This talk will focus on more basic issues such as
telling which genes' expression levels are up, down or essentially
unchanged in treatment/control comparisons, both within and across 
experiments; assigning a precision to measured intensity changes (on
the log scale); and whether different ways of preprocessing the data
(spot identification, background adjustment, color normalization) make 
any discernible difference to the foregoing.

Slides: Download [pdf files] [ps file]

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Last Updated March 07, 2000
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