Title: Sequencing the transcriptome
Speaker: Serban Nacu, Genentech

With several "next generation" technologies already on the market, the
cost of DNA sequencing is dropping rapidly, and the goal of the $1000
genome appears within reach during the next few years. This opens up
exciting possibilities in biology and medicine.

The new technologies generate massive amounts of data: one sequencing
run can produce more than one billion base pairs. The structure of
these large data sets is not well understood. We discuss some of the
relevant statistical and computational issues, focusing on the use of
sequencing to analyze gene expression.