| RMA expression measure (Introduction and Papers) |
The RMA (Robust Multichip Average) expression measure is for Affymetrix Genechip? arrays. It fits a robust linear model at the probe level. We have prepared some papers discussing the RMA methodology.
- Irizarry, RA, Hobbs, B, Collin, F, Beazer-Barclay, YD, Antonellis, KJ, Scherf, U, Speed, TP (2003)
Exploration, Normalization, and Summaries of High Density Oligonucleotide Array Probe Level Data. Biostatistics Vol. 4, Number 2: 249-264
[Abstract,
PDF,
PS,
Complementary Color Figures-PDF,
Software]
- Bolstad, B.M., Irizarry R. A., Astrand, M., and Speed, T.P. (2003)
A Comparison of Normalization Methods for High Density Oligonucleotide Array Data Based on Bias and Variance. Bioinformatics 19(2):185-193
[PDF preprint,
Supplementary information]
- Rafael. A. Irizarry, Benjamin M. Bolstad, Francois Collin, Leslie M. Cope, Bridget Hobbs and Terence P. Speed (2003)
Summaries of Affymetrix GeneChip probe level data Nucleic Acids Research 31(4):e15
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