Stat 260: Statistics in Genetics

T. P. Speed, S. K. McWeeney

Week 13 part II: Molecular Evolution: Substitution Models and Phylogenies

• Substitution Models
  • Background
  • The Problem of Multiple Substitutions
  • Derivation of Jukes-Cantor Correction using Kimura 3 parameter
• Phylogenetic Methods
  • Background
  • Parsimony Methods
  • Likelihood Methods
• References
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