Stat 260: Statistics in Genetics

T. P. Speed, Christina Muirhead

Week 13: Molecular Evolution, part 1

• Background
• Trees from molecules
  • Example: globin genes
  • Gene trees vs. species trees
  • Choice of gene
  • Example: Alu elements
• Evolutionary models
  • The Neutral Theory
  • Wright-Fisher reproduction
  • Substitution rate
    • Molecular clocks
    • Other results from neutral models
  • Selection models
• References
• About this document ...